Quantitative online sheath-flow surface enhanced Raman spectroscopy detection for liquid chromatography.
نویسندگان
چکیده
Sheath-flow surface-enhanced Raman spectroscopy (SERS) was used for online detection and quantification of small molecules separated by liquid chromatography. A mixture of model metabolites (thiamine, folic acid, and riboflavin) was separated and characterized by UV-Vis and SERS detectors connected in series. Acetonitrile in the mobile phase provided an internal standard enabling quantitative detection across SERS experiments.
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ورودعنوان ژورنال:
- The Analyst
دوره 141 12 شماره
صفحات -
تاریخ انتشار 2016